8:00 am Conference Registration & Welcome Coffee

8:50 am Chair’s Opening Remarks

Catalyzing Portfolio Success Through Unveiling the Power of Tumor Microenvironment Dynamics

9:00 am From Images to Insights Revolutionize biomarker selection

  • Maha Rahim Scientific Manager, Insights Delivery, Enable Medicine, Inc.


  • Join Enable Medicine in discussing the importance of identifying high-quality biomarkers, and how multiplex immunofluorescence (mIF) can help select those that correlate more strongly with patient outcomes
  • Deep dive into mIF applications: Learn how a 51-plex protein panel covering a range of functional and tumor microenvironment-related biomarkers helped to identify cell types that are up or downregulated in different disease states and to uncover nuanced spatial relationships between cells
  • Stay at the forefront of immuno-oncology research: Spatial profiles can enable discovery of key biomarkers and high accuracy prediction of treatment outcomes – it is vital to equip your research with a powerful toolkit to elevate and accelerate your research and discovery

9:30 am Panel Discussion: Guiding Immuno-Oncology Breakthroughs with Protein Markers & Advanced Bioinformatics

  • Mike Damore Translational Oncology Lead, Pfizer
  • Jack Chen Scientific Director Precision Medicine, Abbvie
  • Qi Cai Director - Cell Biology, Kite Pharma


• Uncovering the latest developments in identifying and characterizing protein markers that play pivotal roles in immune responses against cancer

• Discussing state-of-the-art bioinformatics tools and computational approaches for analyzing complex protein data, facilitating biomarker discovery, and predicting treatment responses

• Applying protein markers and bioinformatics tools in guiding immuno-oncology research, patient-specific treatment selection, and monitoring clinical responses

10:00 am Allogeneic Stem Cell-Based Platforms to Potentiate & Deliver Oncolytic Virus Therapies

  • Boris Minev President - Medical & Scientific Affairs, Calidi Biotherapeutics Inc.


• Protecting oncolytic viruses from inactivation by complement, blocking antibodies and innate immune cells

• Supporting oncolytic viral amplification inside the stem cells

• Modifying tumor microenvironment by inducing transient immune modulation suppression to allow effective tumor cell targeting and viral amplification at the tumor sites for an extended period

10:30 am Morning Break & Networking

11:00 am Accelerating Discoveries in Spatial Biology through the Illumina Ecosystem


Bench to Bedside: Genomics driven innovation across the drug development pipeline

Do more: Tools to generate more data using Illumina and partner platforms

Gain Insights: Multi-resolution omics to understand immunotherapeutic response

11:30 am Unlocking Immuno-Oncology Advancements: How Spatial Biology Fuels Biomarker and Target Discovery through Granular Characterization of TMEs


  • Characterizing the spatial organization of Tumor Microenvironments to gain a granular understanding of Solid Tumor Biology
  • Discovering the cross-talk between tumor, lymphoid, myeloid and stromal components of TMEs via integrative Spatial Biology to disentangle anti-tumor immune responses.
  • Leveraging a wholistic understanding of TME for advancement of biomarker and novel target discovery.

12:00 pm Linking TME to systemic blood profiling with 3D genetics using EpiSwitchÒ Platform

  • Ewan Hunter Chief Data Officer, Oxford BioDynamics plc


  • What is 3d genomic and why it's important for understanding local and global molecular communication?
  • OBD data and analytical approach to reveal systematic and local TME relationship
  • Development of a 3D genomic Check-point-inhibitor assay to inform about responsive tumours

12:30 pm Lunch Break & Networking

Building Data Analysis Pipelines in Spatial Biology to Empower Insights

1:30 pm Optimization of An Integrated MultiOmyx-RNAscope Hyperplex Assay for Co-Detection and Characterization of Multiple Protein and RNA biomarkers Within the Tumor Microenvironment (TME)


• The Integrated MultiOmyx-RNAscope assay allows for simultaneous analysis of RNA/protein in the TME and is a powerful tool for mapping CAR-T cells or identifying the cellular source of secreted proteins (e.g. cytokines)

• A precision study of the V2 assay using 3 CRC samples demonstrates it is a robust and sensitive planform for co-detection of RNA/protein in a single FFPE sample

• The Integrated MultiOmyx-RNAscope assay V2 shows improved biomarker signal/noise and detection

2:00 pm Roundtable Discussion


This interactive session gives you the opportunity to be part of the discussion, share ideas, and learn from your peers.

Choose the table most relevant to you, and get ready to be part of this conversation:

  • Platform Selection
  • Using AI/ML in Spatial Biology

2:30 pm Afternoon Break & Networking

3:00 pm Validating Spatial Biology Technologies for Optimal Clinical Impact


• Diving into the significance of validating spatial biology techniques to guarantee their accuracy

• Exploring strategies and best practices to ensure the reproducibility of spatial biology results

• Meeting the rigorous standards required for clinical settings, aligning research outcomes with practical application

3:30 pm Understanding Bioinformatics & Computational Tools for Spatial Data Analysis

  • Si Wu Senior Bioinformatics Scientist II, Computational Oncology, Abbvie


• Exploring the fundamentals of spatial data analysis, including data preprocessing, quality control, and integration

• Gaining insights into the unique challenges and opportunities presented by spatial biology datasets

• Learning how to use state-of-the-art software to extract meaningful insights from complex spatial datasets

4:00 pm Chair’s Closing Remarks

4:10 pm End of Day Two

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